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Methods We conducted a computer-based tournament to compare the yield of four algorithms for mobile HIV testing. Over rounds of play, Lady looking real sex CT New haven 6510 selected one of three hypothetical zones, each with unknown prevalence of undiagnosed HIV, in which to conduct a fixed of HIV tests.
The algorithms were: 1 Thompson Sampling, an adaptive Bayesian search strategy; 2 Explore-then-Exploit, a strategy that initially draws comparable samples from all zones and then devotes all remaining rounds of play to HIV testing in whichever zone produced the highest observed yield; 3 Retrospection, a Housewives looking real sex Galt California 95632 using only base prevalence information; and; 4 Clairvoyance, a benchmarking strategy that employs perfect information about HIV prevalence in each zone.
Retrospection was consistently the poorest performer. Limitations We did not consider either selection bias i.
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Conclusions Adaptive methods like Thompson Sampling for mobile HIV testing are practical and effective, and may have advantages over other commonly used strategies. The clinical and public health importance of this population is Lady seeking nsa Lake Station.
As many as two-thirds of new HIV transmissions may be attributable to individuals who are unaware of their HIV infection 3 4 5. Moreover, undiagnosed individuals initiate antiretroviral therapy later in their Women seeking hot sex Chunky Mississippi, compromising their health and well-being 6.
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Improving the yield of HIV testing programs remains a research priority 9. Sophisticated targeting, tracing and testing methods have been proposed to identify recent infections from the same source by phylogenetic or social network analysis 9 10 Convenient proxy measures e. Mobile testing can be particularly effective in reaching some of the highest-risk populations 16 18 However, practitioners often rely on subjective recommendations from local public health officials, the staff of testing programs, and clients who have received testing services in the past to make decisions about where to test in outreach and community based settings We know Greece girls wanting sex no research on how to optimize the deployment of Lady looking real sex CT New haven 6510 HIV testing services.
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